Dr. Ivy Razmus | Reducing Pressure Injuries in Hospitalized Children and Babies

Dr. Ivy Razmus | Reducing Pressure Injuries in Hospitalized Children and Babies

The development of pressure injuries in hospital patients is a regular occurrence, and certain areas of the body are more susceptible. Although there is abundant research on pressure injuries in adult patients, studies relating to infant and child patients are lacking. Dr. Ivy Razmus at the University of Detroit Mercy has conducted extensive research on the prevention of pressure injuries in patients under the age of 12 years. She highlights the crucial role of advanced practice nurses in managing this widespread problem.

Pulque: The Ancient Drink That Could Shape the Future of Health

Pulque: The Ancient Drink That Could Shape the Future of Health

Pulque, an ancient Mexican beverage, is making waves in the scientific community—not just as a cultural relic, but as a potential health-boosting powerhouse. A team of researchers, including Prof. Rogelio Valadez-Blanco, Dr. Yesica Ruiz-Ramírez, and Prof. Paula Guadarrama-Mendoza, from Universidad Tecnológica de La Mixteca, has been investigating the hidden potential of the bacteria found in this traditional drink. Their findings suggest that pulque’s naturally occurring lactic acid bacteria could play a key role in promoting gut health and even combating harmful pathogens that cause foodborne illnesses.

Dr. Robert Kass | Beating arrhythmias with a heart in a dish

Dr. Robert Kass | Beating arrhythmias with a heart in a dish

In the future, doctors will be able to create tiny replicas of your tissues in the lab, and then test them against a range of drugs, revealing exactly which treatments would work best for you before you even visit a drug store. This future of personalised medicine is driven by researchers such as Dr. Robert Kass of the Columbia University Medical Center. Kass and colleagues have pioneered the use of stem cells to develop personalized treatments for a genetic heart condition that disrupts normal heart rhythms. The researchers reprogrammed a patient’s skin cells into stem cells called induced pluripotent stem cells (or iPSCs for short), and they then induced the iPSCs to turn into heart cells. This allowed the research team to study how genetic mutations in the resulting heart cells affect the heart’s ion channels. Their research revealed that a mutation in a specific sodium channel was causing dangerous heart rhythms and that combining the drug mexiletine with a pacemaker device to increase heart rate, provided an effective and personalised treatment.

Dr James E. Goldman | Dr Osama Al-Dalahmah – Confronting the Challenge of Huntington Disease

Dr James E. Goldman | Dr Osama Al-Dalahmah – Confronting the Challenge of Huntington Disease

Huntington disease (HD) is an inherited and progressive neurological disorder which is currently fatal. Dr James E. Goldman and Dr Osama Al-Dalahmah, both at Columbia University, USA, are utilising new techniques in molecular biology to better understand the brain pathology associated with HD. Their vision is to develop therapeutics that can slow the progression of the disease, and ultimately, treat and even prevent it.

Saffiatou Darboe | Rising Above Resistance: How Bacterial Research is Saving Lives in The Gambia

Saffiatou Darboe | Rising Above Resistance: How Bacterial Research is Saving Lives in The Gambia

Antimicrobial resistance (or AMR for short) is a pressing global health challenge that poses significant risks, particularly in low- and middle-income countries. The extensive research conducted by Saffiatou Darboe of the London School of Hygiene and Tropical Medicine, The Gambia, and her colleagues, has been pivotal in understanding and addressing this issue within The Gambia and other regions in sub-Saharan Africa. This episode delves into four comprehensive studies conducted by Darboe and colleagues, shedding light on the impact of AMR, the importance of antibiograms, and specific outbreaks of resistant pathogens.

Prof. Miranda Reed | Shaping Young Minds: How Prenatal Cannabis Use Affects Brain Development

Prof. Miranda Reed | Shaping Young Minds: How Prenatal Cannabis Use Affects Brain Development

As cannabis prohibition begins to unravel across the world, cannabis use has become more common and normalised. Researchers are assessing the impact of this on vulnerable populations, such as pregnant women. Strikingly, cannabis is among the most commonly used substances during pregnancy, raising serious concerns about its effects on unborn children and the long-term consequences this could have. Prof. Miranda Reed of Auburn University, and colleagues, have assessed how cannabis exposure in the womb can affect brain development and cognitive abilities, such as memory.