Emerging Treatment Options in Inflammatory Bowel Disease

Nov 23, 2020 | health and medicine, Karger Publishers

In Collaboration With

Original Article Reference

This SciPod is a shortened and simplified summary of ‘Emerging Treatment Options in Inflammatory Bowel Disease’, published by Karger Publishers https://doi.org/10.1159/000507782

The complete original works are available at www.karger.com

About this episode

Inflammatory bowel disease (IBD) is a group of gastrointestinal conditions affecting almost 7 million people globally, and this incidence is rising. While treatments have improved over the last century, many patients do not respond sufficiently, especially those with moderate to severe levels of the disease. Novel drugs that restrain the immune system and reduce inflammation are being developed with the hope of improving patient outcomes. Dr Benjamin Misselwitz at Island Hospital of Bern and Bern University and his colleagues have conducted a comprehensive review of the emerging therapies and make recommendations for improving treatment for a wider range of patients.

 

 

 

This work is licensed under a Creative Commons Attribution 4.0 International LicenseCreative Commons License

What does this mean?

Share: You can copy and redistribute the material in any medium or format

Adapt: You can change, and build upon the material for any purpose, even commercially.

Credit: You must give appropriate credit, provide a link to the license, and indicate if changes were made.

Related episodes

Dr. Ivan Schewitz | Pectus Excavatum: Minimally Invasive Repair, The Nuss Procedure

Dr. Ivan Schewitz | Pectus Excavatum: Minimally Invasive Repair, The Nuss Procedure

For a long time, deformities of the chest wall, such as pectus excavatum, a condition where the chest appears to have sunken, remained untreated or were treated using crude and invasive techniques. However, thanks to innovations led by surgeons such as Prof. Donald Nuss of Eastern Virginia Medical School, these procedures have undergone a remarkable transformation. Such work has shifted the paradigm from radical surgery to minimally invasive solutions, changing lives and restoring confidence for countless patients. Now, a Review Article published in the African Journal of Thoracic and Critical Care Medicine, and co-authored by Prof. Donald Nuss and Dr. Ivan Schewitz of the Department of Cardiothoracic Surgery at the University of Pretoria, South Africa, charts the remarkable progress in treating pectus excavatum.

Dr. Mabrouka Abuhmida | From Shame to Support: Mental Health Stigma in Conservative Communities

Dr. Mabrouka Abuhmida | From Shame to Support: Mental Health Stigma in Conservative Communities

In many regions around the globe, common mental health issues are cloaked in secrecy by those who experience them, and are frequently stigmatized and misunderstood by others. This is a particularly serious issue in conservative communities, where cultural and religious values have significant effects on the provision and use of appropriate mental health care resources. In a new mini-review article published in the journal Frontiers in Public Health, Dr. Mabrouka Abuhmida, Dr. Wendy Booth and Dr. Felix Anyanwu of the University of South Wales in the UK, have explored this critical topic, revealing the damaging impact of stigma in such communities, and exploring new solutions to enable adequate mental healthcare in this context.

Caroline Kingdon | From Stigma to Support: A New Approach to ME/CFS Treatment in the UK

Caroline Kingdon | From Stigma to Support: A New Approach to ME/CFS Treatment in the UK

Imagine living with an illness that can sap your energy levels so completely that even day-to-day tasks, such as doing laundry, walking the dog, or even getting out of bed can be insurmountable challenges. To make matters worse, this illness is not well understood either by the public or by medical staff, and is often dismissed and stigmatised, making it difficult to find understanding or treatment. This is the unfortunate lived experience of many people with myalgic encephalomyelitis/chronic fatigue syndrome (or ME/CFS for short). In a recent Communication article, researcher Caroline Kingdon of the London School of Hygiene and Tropical Medicine, and colleagues, discuss this misunderstood condition through the prism of the 2021 guideline for the treatment of those with ME/CFS, which have been published by the UK’s National Institute for Health and Care Excellence (or NICE for short). Their article aims to inform primary caregivers about the NICE guideline, and, happily, reveals that the new guideline prioritises an overdue shift toward compassionate and patient-focused care for ME/CFS.

Dr. Roberta Martinelli | Sepsis and the Silent Battle Within: Neutrophils’ Role in Sepsis-Related Complications

Dr. Roberta Martinelli | Sepsis and the Silent Battle Within: Neutrophils’ Role in Sepsis-Related Complications

Sepsis is a critical illness that begins with a simple infection and degenerates into a severe and dysregulated immune response that affects the whole body. This significant immune reaction typically causes widespread inflammation and can progress very rapidly. This can result in serious damage to tissues and organs, potentially leading to organ failure and death. Despite the severity of sepsis and its frequent poor prognosis, effective treatments are still elusive, and many sepsis patients remain at high risk of death and serious complications. Part of the issue is the complex cascade of cellular and biochemical events that underlie sepsis, which has made it difficult to obtain a comprehensive overview of the illness from which to design an effective treatment. Dr. Roberta Martinelli, Executive Director of Stromal Immunology and Early Discovery, Discovery Immunology, Merck, and colleagues, have published a study in the journal iScience which reveals new insights into the complex biological milieu underlying sepsis, and uncovers pathways and potential treatment targets that could change how we diagnose and treat this life-threatening illness.